Carvedilol na insuficiencia cardiaca


Main / Nasal Decongestants / Carvedilol na insuficiencia cardiaca

Métodos -Avaliados em estudo duplo-cego randômi- co, com grupo placebo-controle, 30 pacientes (7 mulhe- res) com insuficiência cardíaca classe funcional II a III, idades de 28 a 66 (média 43±9) anos e fração de ejeção do ventrículo esquerdo de 8% a 35%. Adicionado carvedilol para 20 pacientes e placebo para 10 à. carvedilol, que exerce bloqueio adre- nérgico múltiplo (beta-1, beta-2 e alfa-1), além de efeitos antioxidantes e antiproliferativos, podem ser impor- tantes na inibição da deterioração progressiva da disfunção ventricular esquerda e da insuficiência cardíaca, porém deve ser assinalado que bloqueadores beta-1 seletivos.

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Purpose - The effects of β-blockers on severe heart failure are not well known. We investigated the effects of carvedilol (β1,β2,α1-blocker) on symptoms, functional class (FC), and left ventricular function in patients with refractory heart failure. Methods - We studied 21 patients, mean age 56±10 years, 9 in FC IV, e 12 in FC III. propranolol em substituição ao carvedilol em portadores de. IC clinicamente estáveis. Métodos. Casuística. Foram, prospectivamente, investigados 29 pacientes portadores de insuficiência cardíaca (IC), definida conforme os critérios de Framingham14, em seguimento clínico na. Clínica de Insuficiência Cardíaca do.

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